sulfisomidine

Also known as N(1)-(2,6-Dimethyl-4-pyrimidinyl)sulfanilamide, Sulphasomidine, 2,6-Dimethyl-4-sulfanilamidopyrimidine, 6-(p-Aminobenzenesulfonyl)amino-2,4-dimethylpyrimidine, 6-(p-Aminobenzenesulfonamido)-2,4-dimethylpyrimidine, Sulfasomidine, Sulfaisodimidine, 2,4-Dimethyl-6-sulfanilamidopyrimidine

Sulfisomidine (INN), also known as sulphasomidine (BAN until 2003), sulfamethin and sulfaisodimidine, is a sulfonamide antibacterial. It is closely related to sulfadimidine.

In the Vinony graph

Vinony's link graph records 119 inbound references to sulfisomidine, and connects out to sulfamethazine, antibiotic and fidaxomicin.

It sits within the topics Chemical pages without DrugBank identifier, Drugboxes which contain changes to verified fields and Drugs with no legal status.

Vinony links it to 10 Wikipedia language editions.

Chemical data

Formula: C12H14N4O2S
Molecular weight: 278.33 g/mol
IUPAC name: 4-amino-N-(2,6-dimethylpyrimidin-4-yl)benzenesulfonamide
SMILES: CC1=CC(=NC(=N1)C)NS(=O)(=O)C2=CC=C(C=C2)N
InChIKey: YZMCKZRAOLZXAZ-UHFFFAOYSA-N
XLogP: 1.2
Polar surface area: 106 Å²
H-bond donors: 2
H-bond acceptors: 6
Formal charge: 0

via PubChem

Drug data · ChEMBL

Withdrawn

Max clinical phase: Approved
Molecule type: Small molecule
Indications: bacterial disease

via ChEMBL · EBI

Research

180 papers

SULFISOMIDINE.Journal of the American Medical Association · 1957
Sulfisomidine in the treatment of pertussis.California medicine · 1956
[Dosage of sulfisomidine].Arzneimittel-Forschung · 1969
Supramolecular aggregates formed by sulfadiazine and sulfisomidine inclusion complexes with α- and β-cyclodextrins.Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy · 2014
UV-Fenton degradation of diclofenac, sulpiride, sulfamethoxazole and sulfisomidine: Degradation mechanisms, transformation products, toxicity evolution and effect of real water matrix.Chemosphere · 2020

via PubMed

Wikidata facts

Subclass of: chemical compound
Mass: 278.084

Show 3 more facts

chemical formula: C₁₂H₁₄N₄O₂S
canonical SMILES: CC1=CC(=NC(=N1)C)NS(=O)(=O)C2=CC=C(C=C2)N
Commons category: Sulfisomidine

Sources (2)

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Encyclopedic overview

2 sections

Contents

References
External links

Sulfisomidine (INN), also known as sulphasomidine (BAN until 2003), sulfamethin and sulfaisodimidine, is a sulfonamide antibacterial. It is closely related to sulfadimidine.

==References==

Excerpted from Wikipedia’s “sulfisomidine” article, available under the CC BY-SA 4.0 licence.