SYT1

Also known as P65, SVP65, SYT, synaptotagmin 1, BAGOS

Synaptotagmin-1 is a protein that in humans is encoded by the SYT1 gene.

Gene data

SYT1

Name: synaptotagmin 1
Type: protein-coding
Aliases: BAGOS, P65, SVP65, SYT

This gene encodes a member of the synaptotagmin protein family. The synaptotagmins are integral membrane proteins of synaptic vesicles that serve as calcium sensors in the process of vesicular trafficking and exocytosis. The encoded protein participates in triggering neurotransmitter release at the synapse in response to calcium binding. Mutations in this gene are associated with Baker-Gordon syndrome. [provided by RefSeq, Jan 2023].

via MyGene.info

Wikidata facts

Image: Protein SYT1 PDB 1byn.png

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Article

5 sections

Contents

Function
Interactions
Clinical Significance
References
Further reading

Synaptotagmin-1 is a protein that in humans is encoded by the SYT1 gene.

== Function == Synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as sensors for calcium ions (Ca2+) in the process of vesicular trafficking and exocytosis. Calcium ion binding to synaptotagmin I participates in triggering neurotransmitter release at the synapse. [Supplied by OMIM]