TAAR2
Sign in to saveAlso known as GPR58, taR-2, trace amine associated receptor 2, trace amine associated receptor 2 (gene/pseudogene)
Trace amine-associated receptor 2 (TAAR2), formerly known as G protein-coupled receptor 58 (GPR58), is a protein that in humans is encoded by the TAAR2 gene. TAAR2 is co-expressed with Gα proteins; however, its signal transduction mechanisms have not been determined.
Gene data
TAAR2- Name
- trace amine associated receptor 2
- Type
- protein-coding
- Aliases
- GPR58, taR-2
Predicted to enable trace-amine receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
via MyGene.info
Gene · Ensembl
trace amine associated receptor 2
- Symbol
- TAAR2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 6:132,617,022-132,624,275
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 110760
- exact match
- identifiers.org/ncbigene/9287
- genomic start
- 132938161
- cytogenetic location
- 6q23.2
- genomic end
- 132945414
Sources (4)
via Wikidata · CC0
~3 min read
Article
7 sectionsContents
- Tissue distribution
- Involvement in the functioning of monoamine systems
- Involvement in adult neurogenesis
- Involvement in immune cell migration and function
- Possible Ligands
- See also
- References
Trace amine-associated receptor 2 (TAAR2), formerly known as G protein-coupled receptor 58 (GPR58), is a protein that in humans is encoded by the TAAR2 gene. TAAR2 is co-expressed with Gα proteins; however, its signal transduction mechanisms have not been determined.
== Tissue distribution == Human TAAR2 (hTAAR2) is expressed in the cerebellum, olfactory sensory neurons in the olfactory epithelium, and leukocytes (i.e., white blood cells), among other tissues. hTAAR1 and hTAAR2 are both required for white blood cell activation by trace amines in granulocytes.