TAF6

Name

TATA-box binding protein associated factor 6

Type

protein-coding

Position

100,106,876–100,127,187 (−)

Aliases

ALYUS, MGC:8964, TAF(II)70, TAF(II)80, TAF2E, TAFII-70, TAFII-80, TAFII70, TAFII80, TAFII85

Ensembl

ENSG00000106290

RefSeq RNA

NM_001190415.2, NM_001364998.1, NM_001364999.1, NM_001365000.1, NM_001365001.1

RefSeq protein

NP_001177344.1, NP_001351927.1, NP_001351928.1, NP_001351929.1, NP_001351930.1

Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes one of the smaller subunits of TFIID that binds weakly to TBP but strongly to TAF1, the largest subunit of TFIID. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010].

via MyGene.info

Gene · Ensembl

TATA-box binding protein associated factor 6

Symbol

TAF6

Biotype

Protein coding

Organism

Homo sapiens

Location

7:100,106,876-100,127,187

Strand

Reverse (−)

Assembly

GRCh38

Wikidata facts

Instance of

gene

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