TAF8
Sign in to saveAlso known as 43, II, TAF, TAFII-43, TAFII43, TBN, TATA-box binding protein associated factor 8, TAF(II)43
Transcription initiation factor TFIID subunit 8 is a protein that in humans is encoded by the TAF8 gene.
In the Vinony graph
Within Vinony's link graph, TAF8 is referenced by 3 other articles, and connects out to PubMed, human chromosome 6 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 6.
Its subject is documented across 5 Wikipedia language editions.
Gene data
TAF8- Name
- TATA-box binding protein associated factor 8
- Type
- protein-coding
- Position
- 42,050,513–42,087,461 (+)
- Aliases
- II, NEDMLHB, TAF, TAF(II)43, TAFII-43, TAFII43, TBN
- Ensembl
- ENSG00000137413
- RefSeq RNA
- NM_001410906.1, NM_001410907.1, NM_001438057.1, NM_001438580.1, NM_001438581.1
- RefSeq protein
- NP_001397835.1, NP_001397836.1, NP_001424986.1, NP_001425509.1, NP_001425510.1
This gene encodes one of several TATA-binding protein (TBP)-associated factors (TAFs), which are integral subunits of the general transcription factor complex TFIID. TFIID recognizes the core promoter of many genes and nucleates the assembly of a transcription preinitiation complex containing RNA polymerase II and other initiation factors. The protein encoded by this gene contains an H4-like histone fold domain, and interacts with several subunits of TFIID including TBP and the histone-fold protein TAF10. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
TATA-box binding protein associated factor 8
- Symbol
- TAF8
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 6:42,050,513-42,087,461
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 11094
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/129685
- genomic end
- 42055199
- genomic start
- 42018251
- chromosome
- human chromosome 6
- cytogenetic location
- 6p21.1
- expressed in
- appendix
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Clinical significance
- References
- Further reading
Transcription initiation factor TFIID subunit 8 is a protein that in humans is encoded by the TAF8 gene.
This gene encodes one of several TATA-binding protein (TBP)-associated factors (TAFs), which are integral subunits of the general transcription factor complex TFIID. TFIID recognizes the core promoter of many genes and nucleates the assembly of a transcription preinitiation complex containing RNA polymerase II and other initiation factors. The protein encoded by this gene contains an H4-like histone fold domain, and interacts with several subunits of TFIID including TBP and the histone-fold protein TAF10. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
Excerpted from Wikipedia’s “TAF8” article, available under the CC BY-SA 4.0 licence.