GTF2E1

Also known as FE, TF2E1, TFIIE-A, general transcription factor IIE subunit 1

General transcription factor IIE subunit 1 (GTF2E1), also known as transcription initiation factor IIE subunit alpha (TFIIE-alpha), is a protein that in humans is encoded by the GTF2E1 gene.

In the Vinony graph

Vinony's link graph records 811 inbound references to GTF2E1, and connects out to PubMed, human chromosome 3 and Ensembl genome database project.

It is catalogued under topics including Genes on human chromosome 3 and Transcription factors.

Vinony links it to 5 Wikipedia language editions.

Gene data

GTF2E1

Name: general transcription factor IIE subunit 1
Type: protein-coding
Position: 120,742,370–120,783,368 (+)
Aliases: FE, TF2E1, TFIIE-A
Ensembl: ENSG00000153767
RefSeq RNA: NM_005513.3
RefSeq protein: NP_005504.2

Enables RNA polymerase II general transcription initiation factor activity. Involved in transcription by RNA polymerase II. Located in cytosol and nucleoplasm. Part of transcription factor TFIID complex and transcription preinitiation complex. [provided by Alliance of Genome Resources, Apr 2022]

Gene Ontology

Biological process

transcription by RNA polymerase II transcription initiation at RNA polymerase II promoter transcription initiation at RNA polymerase II promoter transcription initiation at RNA polymerase II promoter RNA polymerase II preinitiation complex assembly

Molecular function

protein binding RNA polymerase II general transcription initiation factor activity

Cellular component

nucleus nucleus nucleus nucleoplasm nucleoplasm transcription factor TFIID complex transcription factor TFIIE complex transcription factor TFIIE complex

Pathways

Basal transcription factors - Homo sapiens (human)Viral carcinogenesis - Homo sapiens (human)HIV Life Cycle Late Phase of HIV Life Cycle HIV Infection Disease HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome Infectious disease

via MyGene.info

Gene · Ensembl

general transcription factor IIE subunit 1

Symbol: GTF2E1
Biotype: Protein coding
Organism: Homo sapiens
Location: 3:120,742,370-120,783,368
Strand: Forward (+)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene
Image: PDB 1vd4 EBI.jpg

Show 8 more facts

HomoloGene ID: 38062
found in taxon: Homo sapiens
exact match: identifiers.org/ncbigene/2960
genomic end: 120501916
genomic start: 120461484
chromosome: human chromosome 3
cytogenetic location: 3q13.33
expressed in: islet of Langerhans

Sources (4)

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Encyclopedic overview

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Contents

See also
References
Further reading

General transcription factor IIE subunit 1 (GTF2E1), also known as transcription initiation factor IIE subunit alpha (TFIIE-alpha), is a protein that in humans is encoded by the GTF2E1 gene.

== See also == Transcription factor II E

Excerpted from Wikipedia’s “GTF2E1” article, available under the CC BY-SA 4.0 licence.