TGFA

Also known as TFGA, transforming growth factor alpha, Transforming growth factor - α

protein-coding gene in the species Homo sapiens

Gene data

TGFA

Name: transforming growth factor alpha
Type: protein-coding
Position: 70,447,284–70,554,193 (−)
Aliases: TFGA
Ensembl: ENSG00000163235
RefSeq RNA: NM_001099691.3, NM_001308158.2, NM_001308159.2, NM_003236.4
RefSeq protein: NP_001093161.1, NP_001295087.1, NP_001295088.1, NP_003227.1

This gene encodes a growth factor that is a ligand for the epidermal growth factor receptor, which activates a signaling pathway for cell proliferation, differentiation and development. This protein may act as either a transmembrane-bound ligand or a soluble ligand. This gene has been associated with many types of cancers, and it may also be involved in some cases of cleft lip/palate. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011].