TGFA
Sign in to saveAlso known as TFGA, transforming growth factor alpha, Transforming growth factor - α
protein-coding gene in the species Homo sapiens
Gene data
TGFA- Name
- transforming growth factor alpha
- Type
- protein-coding
- Position
- 70,447,284–70,554,193 (−)
- Aliases
- TFGA
- Ensembl
- ENSG00000163235
- RefSeq RNA
- NM_001099691.3, NM_001308158.2, NM_001308159.2, NM_003236.4
- RefSeq protein
- NP_001093161.1, NP_001295087.1, NP_001295088.1, NP_003227.1
This gene encodes a growth factor that is a ligand for the epidermal growth factor receptor, which activates a signaling pathway for cell proliferation, differentiation and development. This protein may act as either a transmembrane-bound ligand or a soluble ligand. This gene has been associated with many types of cancers, and it may also be involved in some cases of cleft lip/palate. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
transforming growth factor alpha
- Symbol
- TGFA
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 2:70,447,284-70,554,193
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein TGFA PDB 1mox.png
Show 5 more facts
- HomoloGene ID
- 2431
- exact match
- identifiers.org/ncbigene/7039
- genomic start
- 70447284
- genomic end
- 70781325
- cytogenetic location
- 2p13.3
via Wikidata · CC0