Structure via PubChem · Public domain (PubChem)
tiadenol
Sign in to saveTiadenol is a hypolipidemic agent.
Chemical data
- Formula
- C14H30O2S2
- Molecular weight
- 294.5 g/mol
- IUPAC name
- 2-[10-(2-hydroxyethylsulfanyl)decylsulfanyl]ethanol
- SMILES
- C(CCCCCSCCO)CCCCSCCO
- InChIKey
- WRCITXQNXAIKLR-UHFFFAOYSA-N
- XLogP
- 3.8
- Polar surface area
- 91.1 Ų
- H-bond donors
- 2
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
- Indications
- cardiovascular disease
via ChEMBL · EBI
Research
86 papers- Tiadenol-mediated induction of peroxisomal enzymes in cultured C3H/10T1/2CL8 cells and in chemically transformed C3H/10T1/2 MCA16 cells.International journal of cancer · 1985
- Antilipolytic activity of tiadenol-nicotinate in isolated fat cells: a comparison with its parent drugs.Drugs under experimental and clinical research · 1985
- Experimental studies on pharmacology, metabolism and toxicology with tiadenol-disulfoxide. Dissociation of lipid lowering effects and the induction of peroxisomal and microsomal drug-metabolizing enzymes.Arzneimittel-Forschung · 1987
- Carboxylic metabolites of tiadenol as "proximate" inducers of hepatic peroxisomal beta-oxidation activity.Pharmacological research communications · 1988
- Effects of tiadenol and di-(2-ethylhexyl)phthalate on the metabolism of phosphatidylcholine and phosphatidylethanolamine in the liver of rats: comparison with clofibric acid.Biochemical pharmacology · 1999
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 294.169
Show 3 more facts
- chemical formula
- C₁₄H₃₀O₂S₂
- canonical SMILES
- C(CCCCCSCCO)CCCCSCCO
- subject has role
- hypolipidemic
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
{{Drugbox | Watchedfields = changed | verifiedrevid = 443582176 | IUPAC_name = 2,2'-[decane-1,10-diylbis(thio)]diethanol | image = Tiadenol.png | image_class = skin-invert-image
| tradename = | Drugs.com = | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration =
Excerpted from Wikipedia’s “tiadenol” article, available under the CC BY-SA 4.0 licence.