TLE2
Sign in to saveAlso known as ESG, ESG2, GRG2, transducin like enhancer of split 2, TLE family member 2, transcriptional corepressor
Transducin-like enhancer protein 2 is a protein that in humans is encoded by the TLE2 gene.
Gene data
TLE2- Name
- TLE family member 2, transcriptional corepressor
- Type
- protein-coding
- Position
- 2,997,639–3,047,635 (−)
- Aliases
- ESG, ESG2, GRG2
- Ensembl
- ENSG00000065717
- RefSeq RNA
- NM_001144761.2, NM_001144762.2, NM_001300846.2, NM_003260.5, XM_006722864.3
- RefSeq protein
- NP_001138233.1, NP_001138234.1, NP_001287775.1, NP_003251.2, XP_006722927.1
Enables transcription corepressor activity. Involved in negative regulation of canonical Wnt signaling pathway and negative regulation of transcription, DNA-templated. Located in focal adhesion and nuclear body. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
TLE family member 2, transcriptional corepressor
- Symbol
- TLE2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 19:2,997,632-3,047,635
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 20693
- exact match
- identifiers.org/ncbigene/7089
- genomic end
- 3047633
- genomic start
- 2997639
- cytogenetic location
- 19p13.3
Sources (4)
via Wikidata · CC0
~1 min read
Article
3 sectionsContents
- Interactions
- References
- Further reading
Transducin-like enhancer protein 2 is a protein that in humans is encoded by the TLE2 gene.
==Interactions== TLE2 has been shown to interact with TLE1 and HES1.