TLE1
Sign in to saveAlso known as ESG, ESG1, GRG1, transducin like enhancer of split 1, TLE family member 1, transcriptional corepressor, TLE-1
Transducin-like enhancer protein 1 is a protein that in humans is encoded by the TLE1 gene.
Gene data
TLE1- Name
- TLE family member 1, transcriptional corepressor
- Type
- protein-coding
- Aliases
- ESG, ESG1, GRG1, TLE-1
Enables identical protein binding activity and transcription corepressor activity. Involved in negative regulation of I-kappaB kinase/NF-kappaB signaling; negative regulation of anoikis; and regulation of gene expression. Located in cytosol and nucleoplasm. Part of beta-catenin-TCF complex. [provided by Alliance of Genome Resources, Apr 2022]
via MyGene.info
Gene · Ensembl
TLE family member 1, transcriptional corepressor
- Symbol
- TLE1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 9:81,582,313-81,689,681
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein TLE1 PDB 1gxr.png
Show 5 more facts
- HomoloGene ID
- 21058
- exact match
- identifiers.org/ncbigene/7088
- genomic start
- 84198598
- genomic end
- 81689547
- cytogenetic location
- 9q21.32
Sources (4)
via Wikidata · CC0
~1 min read
Article
3 sectionsContents
- Interactions
- References
- Further reading
Transducin-like enhancer protein 1 is a protein that in humans is encoded by the TLE1 gene.
== Interactions ==