Also known as AML2, CBFA3, PEBP2aC, runt related transcription factor 3, RUNX family transcription factor 3
Runt-related transcription factor 3 is a protein that in humans is encoded by the RUNX3 gene.
This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016].
via MyGene.info
Runt-related transcription factor 3 is a protein that in humans is encoded by the RUNX3 gene.
== Function ==
via Wikidata · CC0
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).