TLE4

Also known as BCE-1, BCE1, E(spI), ESG, ESG4, GRG4, Grg-4, transducin like enhancer of split 4

Transducin-like enhancer protein 4 is a protein that in humans is encoded by the TLE4 gene.

Gene data

TLE4

Name: TLE family member 4, transcriptional corepressor
Type: protein-coding
Position: 79,571,773–79,726,882 (+)
Aliases: BCE-1, BCE1, E(spI), E(spl), ESG, ESG4, GRG4, Grg-4
Ensembl: ENSG00000106829
RefSeq RNA: NM_001282748.2, NM_001282749.2, NM_001282753.2, NM_001282760.2, NM_001351541.2
RefSeq protein: NP_001269677.1, NP_001269678.1, NP_001269682.1, NP_001269689.1, NP_001338470.1

Predicted to enable transcription corepressor activity. Predicted to be involved in negative regulation of canonical Wnt signaling pathway. Predicted to act upstream of or within Wnt signaling pathway; cellular response to leukemia inhibitory factor; and negative regulation of transcription by RNA polymerase II. Located in nucleoplasm. Part of beta-catenin-TCF complex. [provided by Alliance of Genome Resources, Apr 2022]