TLE4
Sign in to saveAlso known as BCE-1, BCE1, E(spI), ESG, ESG4, GRG4, Grg-4, transducin like enhancer of split 4
Transducin-like enhancer protein 4 is a protein that in humans is encoded by the TLE4 gene.
Gene data
TLE4- Name
- TLE family member 4, transcriptional corepressor
- Type
- protein-coding
- Position
- 79,571,773–79,726,882 (+)
- Aliases
- BCE-1, BCE1, E(spI), E(spl), ESG, ESG4, GRG4, Grg-4
- Ensembl
- ENSG00000106829
- RefSeq RNA
- NM_001282748.2, NM_001282749.2, NM_001282753.2, NM_001282760.2, NM_001351541.2
- RefSeq protein
- NP_001269677.1, NP_001269678.1, NP_001269682.1, NP_001269689.1, NP_001338470.1
Predicted to enable transcription corepressor activity. Predicted to be involved in negative regulation of canonical Wnt signaling pathway. Predicted to act upstream of or within Wnt signaling pathway; cellular response to leukemia inhibitory factor; and negative regulation of transcription by RNA polymerase II. Located in nucleoplasm. Part of beta-catenin-TCF complex. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
TLE family member 4, transcriptional corepressor
- Symbol
- TLE4
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 9:79,571,773-79,726,882
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein TLE4 PDB 1gxr.png
Show 5 more facts
- HomoloGene ID
- 38259
- exact match
- identifiers.org/ncbigene/7091
- genomic end
- 82341658
- genomic start
- 82186688
- cytogenetic location
- 9q21.31
Sources (4)
via Wikidata · CC0
~1 min read
Article
3 sectionsContents
- Interactions
- References
- Further reading
Transducin-like enhancer protein 4 is a protein that in humans is encoded by the TLE4 gene.
== Interactions ==