Structure via PubChem · Public domain (PubChem)
tribenoside
Sign in to saveAlso known as GLY401, Tribenosido, Tribenosidum, TBGF
Tribenoside (Glyvenol) is a vasoprotective drug used to treat hemorrhoids. It has mild anti-inflammatory, analgesic, and wound healing properties. Tribenoside stimulates laminin α5 production and laminin-332 deposition to help repair the basement membrane during the wound healing process. It is a mixture of the α- and β-anomers.
In the Vinony graph
Within Vinony's link graph, tribenoside is referenced by 33 other articles, and connects out to medication, circulatory system and hemorrhoid.
Vinony files it under Chemical pages without DrugBank identifier, Drugboxes which contain changes to verified fields and Drugboxes which contain changes to watched fields.
Its subject is documented across 7 Wikipedia language editions.
Chemical data
- Formula
- C29H34O6
- Molecular weight
- 478.6 g/mol
- IUPAC name
- (3R,4R,5R)-5-[(1R)-1,2-bis(phenylmethoxy)ethyl]-2-ethoxy-4-phenylmethoxyoxolan-3-ol
- SMILES
- CCOC1[C@@H]([C@H]([C@H](O1)[C@@H](COCC2=CC=CC=C2)OCC3=CC=CC=C3)OCC4=CC=CC=C4)O
- InChIKey
- ULLNJSBQMBKOJH-VIVFLBMVSA-N
- XLogP
- 3.9
- Polar surface area
- 66.4 Ų
- H-bond donors
- 1
- H-bond acceptors
- 6
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
- Indications
- cardiovascular disease, hemorrhoid
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 478.236
Show 5 more facts
- chemical formula
- C₂₉H₃₄O₆
- canonical SMILES
- CCOC1C(C(C(O1)C(COCC2=CC=CC=C2)OCC3=CC=CC=C3)OCC4=CC=CC=C4)O
- isomeric SMILES
- CCOC1[C@@H]([C@H]([C@H](O1)[C@@H](COCC2=CC=CC=C2)OCC3=CC=CC=C3)OCC4=CC=CC=C4)O
- subject has role
- non-steroidal anti-inflammatory drug
- World Health Organisation international non-proprietary name
- tribenoside
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
Tribenoside (Glyvenol) is a vasoprotective drug used to treat hemorrhoids. It has mild anti-inflammatory, analgesic, and wound healing properties. Tribenoside stimulates laminin α5 production and laminin-332 deposition to help repair the basement membrane during the wound healing process. It is a mixture of the α- and β-anomers.
Tribenoside has been shown to induce drug hypersensitivity syndrome in association with CMV reactivation.
Excerpted from Wikipedia’s “tribenoside” article, available under the CC BY-SA 4.0 licence.