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tribenoside

Structure via PubChem · Public domain (PubChem)

EntityQ533119· pop 7· linked from 33 articles

tribenoside

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Also known as GLY401, Tribenosido, Tribenosidum, TBGF

Tribenoside (Glyvenol) is a vasoprotective drug used to treat hemorrhoids. It has mild anti-inflammatory, analgesic, and wound healing properties. Tribenoside stimulates laminin α5 production and laminin-332 deposition to help repair the basement membrane during the wound healing process. It is a mixture of the α- and β-anomers.

In the Vinony graph

Within Vinony's link graph, tribenoside is referenced by 33 other articles, and connects out to medication, circulatory system and hemorrhoid.

Vinony files it under Chemical pages without DrugBank identifier, Drugboxes which contain changes to verified fields and Drugboxes which contain changes to watched fields.

Its subject is documented across 7 Wikipedia language editions.

Chemical data

Formula
C29H34O6
Molecular weight
478.6 g/mol
IUPAC name
(3R,4R,5R)-5-[(1R)-1,2-bis(phenylmethoxy)ethyl]-2-ethoxy-4-phenylmethoxyoxolan-3-ol
SMILES
CCOC1[C@@H]([C@H]([C@H](O1)[C@@H](COCC2=CC=CC=C2)OCC3=CC=CC=C3)OCC4=CC=CC=C4)O
InChIKey
ULLNJSBQMBKOJH-VIVFLBMVSA-N
XLogP
3.9
Polar surface area
66.4 Ų
H-bond donors
1
H-bond acceptors
6
Formal charge
0

via PubChem

Drug data · ChEMBL

Max clinical phase
Phase 2
Molecule type
Small molecule
Indications
cardiovascular disease, hemorrhoid

via ChEMBL · EBI

Wikidata facts

Mass
478.236
Show 5 more facts
chemical formula
C₂₉H₃₄O₆
canonical SMILES
CCOC1C(C(C(O1)C(COCC2=CC=CC=C2)OCC3=CC=CC=C3)OCC4=CC=CC=C4)O
isomeric SMILES
CCOC1[C@@H]([C@H]([C@H](O1)[C@@H](COCC2=CC=CC=C2)OCC3=CC=CC=C3)OCC4=CC=CC=C4)O
World Health Organisation international non-proprietary name
tribenoside
Sources (3)

via Wikidata · CC0

~1 min read

Encyclopedic overview

1 sections
Contents
  • References

Tribenoside (Glyvenol) is a vasoprotective drug used to treat hemorrhoids. It has mild anti-inflammatory, analgesic, and wound healing properties. Tribenoside stimulates laminin α5 production and laminin-332 deposition to help repair the basement membrane during the wound healing process. It is a mixture of the α- and β-anomers.

Tribenoside has been shown to induce drug hypersensitivity syndrome in association with CMV reactivation.

Excerpted from Wikipedia’s “tribenoside” article, available under the CC BY-SA 4.0 licence.

Available in 7 languages

via Wikidata sitelinks · CC0

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