UBR5

Also known as DD5, EDD, EDD1, HYD, ubiquitin protein ligase E3 component n-recognin 5

E3 ubiquitin-protein ligase UBR5 is an enzyme that in humans is encoded by the UBR5 gene.

In the Vinony graph

Vinony's link graph records 6 inbound references to UBR5, and connects out to PubMed, Ensembl genome database project and protein.

It is catalogued under topics including Genes on human chromosome 8 and Long stubs with short prose.

Vinony links it to 5 Wikipedia language editions.

Gene data

UBR5

Name: ubiquitin protein ligase E3 component n-recognin 5
Type: protein-coding
Position: 102,250,605–102,412,883 (−)
Aliases: DD5, EDD, EDD1, HYD, NEDSBH
Ensembl: ENSG00000104517
RefSeq RNA: NM_001282873.2, NM_015902.6, XM_005250962.6, XM_024447178.2, XM_024447179.2
RefSeq protein: NP_001269802.1, NP_056986.2, XP_005251019.1, XP_024302946.1, XP_024302947.1

This gene encodes a progestin-induced protein, which belongs to the HECT (homology to E6-AP carboxyl terminus) family. The HECT family proteins function as E3 ubiquitin-protein ligases, targeting specific proteins for ubiquitin-mediated proteolysis. This gene is localized to chromosome 8q22 which is disrupted in a variety of cancers. This gene potentially has a role in regulation of cell proliferation or differentiation. [provided by RefSeq, Jul 2008].