VNN2
Sign in to saveAlso known as FOAP-4, GPI-80, vanin 2
Vascular non-inflammatory molecule 2 is a protein that in humans is encoded by the VNN2 gene.
In the Vinony graph
Vinony's link graph records 3 inbound references to VNN2, and connects out to PubMed, human chromosome 6 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 6.
Vinony links it to 6 Wikipedia language editions.
Gene data
VNN2- Name
- vanin 2
- Type
- protein-coding
- Aliases
- FOAP-4, GPI-80
This gene product is a member of the Vanin family of proteins that share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. The encoded protein is a GPI-anchored cell surface molecule that plays a role in transendothelial migration of neutrophils. This gene lies in close proximity to, and in same transcriptional orientation as two other vanin genes on chromosome 6q23-q24. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, May 2011].
via MyGene.info
Gene · Ensembl
vanin 2
- Symbol
- VNN2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 6:132,743,870-132,763,466
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 130041
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/8875
- genomic end
- 133084598
- genomic start
- 133065009
- chromosome
- human chromosome 6
- cytogenetic location
- 6q23.2
- expressed in
- gallbladder
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Vascular non-inflammatory molecule 2 is a protein that in humans is encoded by the VNN2 gene.
This gene product is a member of the Vanin family of proteins which share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response.
Excerpted from Wikipedia’s “VNN2” article, available under the CC BY-SA 4.0 licence.