YWHAB

Name

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta

Type

protein-coding

Position

44,885,676–44,908,532 (+)

Aliases

GW128, HEL-S-1, HS1, KCIP-1, YWHAA

Ensembl

ENSG00000166913

RefSeq RNA

NM_003404.5, NM_139323.4, XM_017028040.2, XM_054323962.1

RefSeq protein

NP_003395.1, NP_647539.1, XP_016883529.1, XP_054179937.1

This gene encodes a protein belonging to the 14-3-3 family of proteins, members of which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals. The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. Two transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008].