ADRA1A

Name

adrenoceptor alpha 1A

Type

protein-coding

Position

26,748,123–26,867,380 (−)

Aliases

ADRA1C, ADRA1L1, ALPHA1AAR

Ensembl

ENSG00000120907

RefSeq RNA

NM_000680.4, NM_001322502.1, NM_001322503.1, NM_001322504.1, NM_033302.3

RefSeq protein

NP_000671.2, NP_001309431.1, NP_001309432.1, NP_001309433.1, NP_150645.2

Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1A-adrenergic receptor. Alternative splicing of this gene generates four transcript variants, which encode four different isoforms with distinct C-termini but having similar ligand binding properties. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

adrenoceptor alpha 1A

Symbol

ADRA1A

Biotype

Protein coding

Organism

Homo sapiens

Location

8:26,748,123-26,867,380

Strand

Reverse (−)

Assembly

GRCh38