아미트리프틸린

Also known as amitryptiline, 5-(gamma-dimethylaminopropylidene)-5H-dibenzo[a,d][1,4]cycloheptadiene, 3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethylpropan-1-amine, 5-(3-dimethylaminopropylidene)-10,11-dihydro-5H-dibenzo[a,d]cycloheptene, 5-(3-dimethylaminopropylidene)-10,11-dihydro-5H-dibenzo[a,d]cycloheptatriene, 10,11-dihydro-N,N-dimethyl-5H-dibenzo(a,d)heptalene-delta(5),gamma-propylamine, 10,11-dihydro-5-(gamma-dimethylaminopropylidene)-5H-dibenzo[a,d]cycloheptene, 10,11-dihydro-N,N-dimethyl-5H-dibenzo[a,d]heptalene-delta(5),gamma-propylamine

삼환계 항우울제

OverviewAI-generated

Amitriptyline is a chemical compound with the formula C₂₀H₂₃N. Its IUPAC name is N,N-dimethyl-3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaenylidene)propan-1-amine. The compound has a mass of 277.183 and a defined daily dose of 75.

Chemical properties include an xlogp of 5, a topological polar surface area of 3.2, and a charge of 0. It has zero hydrogen bond donors and one hydrogen bond acceptor. The canonical SMILES notation for the molecule is CN(C)CCC=C1C2=CC=CC=C2CCC3=CC=CC=C31.

Amitriptyline is referenced by 4,158 other encyclopedia articles. A search for the term in PubMed yields a count of 10,509 entries.

Synthesized by Vinony from 19 facts across 4 sources: Wikidata, PubMed, PubChem, Vinony graph. Generated from structured data (not the Wikipedia text) and checked against those facts — may still contain errors.

Key facts

Drug.Watchedfields: changed
Drug.verifiedrevid: 477169407
Drug.image: Amitriptyline2DACS.svg
Drug.image_class: skin-invert-image
Drug.width: 200
Drug.image2: Amitriptyline-from-picrate-xtal-3D-balls.png
Drug.image_class2: bg-transparent
Drug.width2: 250
Drug.tradename: Elavil, others
Drug.MedlinePlus: a682388
Drug.DailyMedID: Amitriptyline
Drug.pregnancy_AU: C
Drug.routes_of_administration: Oral, intramuscular injection
Drug.class: Tricyclic antidepressant (TCA)
Drug.ATC_prefix: N06
Drug.ATC_suffix: AA09
Drug.legal_AU: S4
Drug.legal_BR: C1

via Wikipedia infobox

Chemical data

Formula: C20H23N
Molecular weight: 277.4 g/mol
IUPAC name: N,N-dimethyl-3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaenylidene)propan-1-amine
SMILES: CN(C)CCC=C1C2=CC=CC=C2CCC3=CC=CC=C31
InChIKey: KRMDCWKBEZIMAB-UHFFFAOYSA-N
XLogP: 5
Polar surface area: 3.2 Å²
H-bond donors: 0
H-bond acceptors: 1
Formal charge: 0