ARAP3
Sign in to saveAlso known as CENTD3, DRAG1, ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 is a protein that in humans is encoded by the ARAP3 gene.
In the Vinony graph
Vinony's link graph records 2 inbound references to ARAP3, and connects out to PubMed, human chromosome 5 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 5.
Vinony links it to 5 Wikipedia language editions.
Gene data
ARAP3- Name
- ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
- Type
- protein-coding
- Position
- 141,653,204–141,682,255 (−)
- Aliases
- CENTD3, DRAG1
- Ensembl
- ENSG00000120318
- RefSeq RNA
- NM_022481.6, XM_005268498.3, XM_005268499.2, XM_005268500.5, XM_011537677.3
- RefSeq protein
- NP_071926.4, XP_005268555.1, XP_005268556.1, XP_005268557.1, XP_011535979.1
This gene encodes a phosphoinositide binding protein containing ARF-GAP, RHO-GAP, RAS-associating, and pleckstrin homology domains. The ARF-GAP and RHO-GAP domains cooperate in mediating rearrangements in the cell cytoskeleton and cell shape. It is a specific PtdIns(3,4,5)P3/PtdIns(3,4)P2-stimulated Arf6-GAP protein. An alternatively spliced transcript has been found for this gene, but its biological validity has not been determined. [provided by RefSeq, Sep 2015].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
- Symbol
- ARAP3
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 5:141,653,204-141,682,255
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 11199
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/64411
- genomic end
- 141682230
- genomic start
- 141032968
- chromosome
- human chromosome 5
- cytogenetic location
- 5q31.3
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- References
- External links
- Further reading
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 is a protein that in humans is encoded by the ARAP3 gene.
This gene encodes a phosphoinositide binding protein containing ARF-GAP, RHO-GAP, RAS-associating, and pleckstrin homology domains. The ARF-GAP and RHO-GAP domains cooperate in mediating rearrangements in the cell cytoskeleton and cell shape. It is a specific PtdIns(3,4,5)P3/PtdIns(3,4)P2-stimulated Arf6-GAP protein. An alternatively spliced transcript has been found for this gene, but its full-length nature has not been determined.
Excerpted from Wikipedia’s “ARAP3” article, available under the CC BY-SA 4.0 licence.