ARAP3
Sign in to saveAlso known as CENTD3, DRAG1, ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 is a protein that in humans is encoded by the ARAP3 gene.
Gene data
ARAP3- Name
- ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
- Type
- protein-coding
- Aliases
- CENTD3, DRAG1
This gene encodes a phosphoinositide binding protein containing ARF-GAP, RHO-GAP, RAS-associating, and pleckstrin homology domains. The ARF-GAP and RHO-GAP domains cooperate in mediating rearrangements in the cell cytoskeleton and cell shape. It is a specific PtdIns(3,4,5)P3/PtdIns(3,4)P2-stimulated Arf6-GAP protein. An alternatively spliced transcript has been found for this gene, but its biological validity has not been determined. [provided by RefSeq, Sep 2015].
via MyGene.info
Gene · Ensembl
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
- Symbol
- ARAP3
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 5:141,653,204-141,682,255
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 11199
- exact match
- identifiers.org/ncbigene/64411
- genomic end
- 141682230
- genomic start
- 141032968
- cytogenetic location
- 5q31.3
Sources (4)
via Wikidata · CC0
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Article
3 sectionsContents
- References
- External links
- Further reading
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 is a protein that in humans is encoded by the ARAP3 gene.
This gene encodes a phosphoinositide binding protein containing ARF-GAP, RHO-GAP, RAS-associating, and pleckstrin homology domains. The ARF-GAP and RHO-GAP domains cooperate in mediating rearrangements in the cell cytoskeleton and cell shape. It is a specific PtdIns(3,4,5)P3/PtdIns(3,4)P2-stimulated Arf6-GAP protein. An alternatively spliced transcript has been found for this gene, but its full-length nature has not been determined.