AKAP5
Sign in to saveAlso known as AKAP75, AKAP79, H21, A-kinase anchoring protein 5
A-kinase anchor protein 5 is a protein that in humans is encoded by the AKAP5 gene.
In the Vinony graph
Within Vinony's link graph, AKAP5 is referenced by 5 other articles, and connects out to PubMed, human chromosome 14 and Ensembl genome database project.
Vinony files it under A-kinase-anchoring proteins and Genes on human chromosome 14.
Its subject is documented across 5 Wikipedia language editions.
Gene data
AKAP5- Name
- A-kinase anchoring protein 5
- Type
- protein-coding
- Position
- 64,465,275–64,474,503 (+)
- Aliases
- AKAP75, AKAP79, H21
- Ensembl
- ENSG00000179841
- RefSeq RNA
- NM_004857.3
- RefSeq protein
- NP_004848.3
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein binds to the RII-beta regulatory subunit of PKA, and also to protein kinase C and the phosphatase calcineurin. It is predominantly expressed in cerebral cortex and may anchor the PKA protein at postsynaptic densities (PSD) and be involved in the regulation of postsynaptic events. It is also expressed in T lymphocytes and may function to inhibit interleukin-2 transcription by disrupting calcineurin-dependent dephosphorylation of NFAT. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
A-kinase anchoring protein 5
- Symbol
- AKAP5
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 14:64,465,275-64,474,503
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 15854
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/9495
- genomic end
- 64941221
- genomic start
- 64932217
- chromosome
- human chromosome 14
- cytogenetic location
- 14q23.3
- expressed in
- prefrontal cortex
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
5 sectionsContents
- Function
- Interactions
- References
- External links
- Further reading
A-kinase anchor protein 5 is a protein that in humans is encoded by the AKAP5 gene.
== Function ==
Excerpted from Wikipedia’s “AKAP5” article, available under the CC BY-SA 4.0 licence.