ARR3
Sign in to saveAlso known as ARRX, cArr, arrestin 3 retinal (X-arrestin), arrestin 3, MYP26
Arrestin-C, also known as retinal cone arrestin-3, is a protein that in humans is encoded by the ARR3 gene.
Gene data
ARR3- Name
- arrestin 3
- Type
- protein-coding
- Chromosome
- X
- Position
- 70,268,305–70,281,840 (+)
- Aliases
- ARRX, MYP26, cArr
- Ensembl
- ENSG00000120500
- RefSeq RNA
- NM_004312.3, XM_047442105.1, XM_054327056.1
- RefSeq protein
- NP_004303.2, XP_047298061.1, XP_054183031.1
The protein encoded by this gene is a non-visual arrestin which binds to agonist-activated, phosphorylated G protein-coupled receptors. This binding uncouples the receptor from the heterotrimeric G protein, resulting in termination of the G protein-coupled receptor signaling. The encoded protein also is a part of the centrosome, interacting with gamma-tubulin to help regulate proper centrosome function. [provided by RefSeq, May 2016].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
arrestin 3
- Symbol
- ARR3
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- Chr X:70,268,305-70,281,840
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein ARR3 PDB 1XEH.png
Show 7 more facts
- HomoloGene ID
- 3182
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/407
- chromosome
- human X chromosome
- genomic end
- 69501690
- genomic start
- 69488155
- cytogenetic location
- Xq13.1
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- See also
- References
- Further reading
- External links
Arrestin-C, also known as retinal cone arrestin-3, is a protein that in humans is encoded by the ARR3 gene.
== See also == Arrestin
Excerpted from Wikipedia’s “ARR3” article, available under the CC BY-SA 4.0 licence.