TSPAN8
Sign in to saveAlso known as CO-029, TM4SF3, tetraspanin 8
Tetraspanin-8 is a protein that in humans is encoded by the TSPAN8 gene.
Gene data
TSPAN8- Name
- tetraspanin 8
- Type
- protein-coding
- Aliases
- CO-029, TM4SF3
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This gene is expressed in different carcinomas. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq, Jul 2008].
via MyGene.info
Gene · Ensembl
tetraspanin 8
- Symbol
- TSPAN8
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 12:71,124,454-71,441,898
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 20968
- exact match
- identifiers.org/ncbigene/7103
- genomic end
- 71835678
- genomic start
- 71518865
- cytogenetic location
- 12q21.1
Sources (4)
via Wikidata · CC0
~1 min read
Article
4 sectionsContents
- Function
- Clinical significance
- References
- Further reading
Tetraspanin-8 is a protein that in humans is encoded by the TSPAN8 gene.
== Function ==