Also known as AM, ATF-IP, MCAF, MCAF1, p621, activating transcription factor 7 interacting protein
Activating transcription factor 7-interacting protein 1 is a protein that in humans is encoded by the ATF7IP gene.
ATF7IP is a multifunctional nuclear protein that associates with heterochromatin. It can act as a transcriptional coactivator or corepressor depending upon its binding partners (summary by Liu et al., 2009 [PubMed 19106100]).[supplied by OMIM, Nov 2010].
via MyGene.info
Activating transcription factor 7-interacting protein 1 is a protein that in humans is encoded by the ATF7IP gene.
==Interactions== ATF7IP has been shown to interact with MBD1. In mice with T cell-specific deletion of Atf7ip, the protein has been shown to play a role in regulating T helper 17 cell (Th17) differentiation due to increased IL-2 production upon stimulation of the T cell receptor (TCR). This TCR stimulation occurs through deposition of H3K9me3, a repressive histone mark.
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).