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Structure via PubChem · Public domain (PubChem)
benzylthiouracil
Sign in to saveBenzylthiouracil (BTU) is an antithyroid preparation. It is a thioamide, closely related to propylthiouracil.
In the Vinony graph
Within Vinony's link graph, benzylthiouracil is referenced by 55 other articles, and connects out to propranolol, sulfur and kidney.
It is catalogued under topics including Antithyroid drugs, Chemical pages without DrugBank identifier and Drugboxes which contain changes to watched fields.
Its subject is documented across 7 Wikipedia language editions.
Chemical data
- Formula
- C11H10N2OS
- Molecular weight
- 218.28 g/mol
- IUPAC name
- 6-benzyl-2-sulfanylidene-1H-pyrimidin-4-one
- SMILES
- C1=CC=C(C=C1)CC2=CC(=O)NC(=S)N2
- InChIKey
- PNXBXCRWXNESOV-UHFFFAOYSA-N
- XLogP
- 1.6
- Polar surface area
- 73.2 Ų
- H-bond donors
- 2
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
- Indications
- Abnormality of the thyroid gland
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 218.051
Show 2 more facts
- chemical formula
- C₁₁H₁₀N₂OS
- canonical SMILES
- C1=CC=C(C=C1)CC2=CC(=O)NC(=S)N2
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- Adverse effects
- References
Benzylthiouracil (BTU) is an antithyroid preparation. It is a thioamide, closely related to propylthiouracil.
==Adverse effects== Benzylthiouracil has been associated with severe adverse effects, notably vasculitis and subsequent ANCA-positive glomerulonephritis, as well as isolated reports of lung damage.
Excerpted from Wikipedia’s “benzylthiouracil” article, available under the CC BY-SA 4.0 licence.