Structure via PubChem · Public domain (PubChem)
betahistine
Sign in to saveAlso known as Betahistina, N-Methyl-2-pyridineethanamine, 2-(beta-Methylaminoethyl)pyridine, N-Methyl-2-(2-pyridinyl)ethanamine, 2-[2-(Methylamino)ethyl]pyridine, Betahistinum, [2-(2-Pyridyl)ethyl]methylamine
thumb|260px|right|Betahistine(12mg) Betahistine, sold under the brand name Serc among others, is an anti-vertigo medication. It is commonly prescribed for balance disorders or to alleviate vertigo symptoms. It was first registered in Europe in 1970 for the treatment of Ménière's disease, but current evidence does not support its efficacy in treating it.
Chemical data
- Formula
- C8H12N2
- Molecular weight
- 136.19 g/mol
- IUPAC name
- N-methyl-2-pyridin-2-ylethanamine
- SMILES
- CNCCC1=CC=CC=N1
- InChIKey
- UUQMNUMQCIQDMZ-UHFFFAOYSA-N
- XLogP
- 0.4
- Polar surface area
- 24.9 Ų
- H-bond donors
- 1
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Research
724 papers- Betahistine in Ménière's Disease or Syndrome: A Systematic Review.Audiology & neuro-otology · 2022
- [Betahistine in vestibular disorders: current concepts and perspectives].Vestnik otorinolaringologii · 2021
- Efficacy and safety of betahistine treatment in patients with Meniere's disease: primary results of a long term, multicentre, double blind, randomised, placebo controlled, dose defining trial (BEMED trial).BMJ (Clinical research ed.) · 2016
- Is Betahistine Effective in the Treatment of Ménière's Disease?The Laryngoscope · 2021
- Betahistine for symptoms of vertigo.The Cochrane database of systematic reviews · 2016
via PubMed
Wikidata facts
- Mass
- 136.1
Show 5 more facts
- chemical formula
- C₈H₁₂N₂
- defined daily dose
- 24
- Commons category
- Betahistine
- canonical SMILES
- CNCCC1=CC=CC=N1
- World Health Organisation international non-proprietary name
- betahistine
via Wikidata · CC0
~9 min read
Article
15 sectionsContents
- Medical uses
- Contraindications
- Adverse effects
- Digestive
- Others
- Pharmacology
- Pharmacodynamics
- Pharmacokinetics
- Chemistry
- Society and culture
- Brand names
- Availability
- United States
- See also
- References
thumb|260px|right|Betahistine(12mg) Betahistine, sold under the brand name Serc among others, is an anti-vertigo medication. It is commonly prescribed for balance disorders or to alleviate vertigo symptoms. It was first registered in Europe in 1970 for the treatment of Ménière's disease, but current evidence does not support its efficacy in treating it.
==Medical uses== Betahistine was once believed to have some positive effects in the treatment of Ménière's disease and vertigo, but more recent evidence casts doubt on its efficacy. Studies of the use of betahistine have shown a reduction in symptoms of vertigo and, to a lesser extent, tinnitus, but conclusive evidence is lacking at present.