BOP1
Sign in to saveAlso known as block of proliferation 1, BOP1 ribosomal biogenesis factor
Ribosome biogenesis protein BOP1 is a protein that in humans is encoded by the BOP1 gene. It is a WD40 repeat-containing nucleolar protein involved in rRNA processing, thereby controlling the cell cycle. It is required for the maturation of the 25S and 5.8S ribosomal RNAs. It may serve as an essential factor in ribosome formation that coordinates processing of the spacer regions in pre-rRNA.
In the Vinony graph
Vinony's link graph records 5 inbound references to BOP1, and connects out to PubMed, human chromosome 8 and Ensembl genome database project.
Vinony files it under Genes on human chromosome 8, Protein domains and Protein pages needing a picture.
Vinony links it to 5 Wikipedia language editions.
Gene data
BOP1- Name
- BOP1 ribosomal biogenesis factor
- Type
- protein-coding
- Position
- 144,262,045–144,291,453 (−)
- Ensembl
- ENSG00000261236
- RefSeq RNA
- NM_015201.5
- RefSeq protein
- NP_056016.1
Enables RNA binding activity. Involved in regulation of cell cycle; regulation of signal transduction by p53 class mediator; and ribosomal large subunit biogenesis. Located in chromosome; nucleolus; and nucleoplasm. Part of PeBoW complex. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
BOP1 ribosomal biogenesis factor
- Symbol
- BOP1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 8:144,262,045-144,291,453
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 6612
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/23246
- chromosome
- human chromosome 8
- genomic start
- 144262045
- genomic end
- 144291438
- cytogenetic location
- 8q24.3
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
5 sectionsContents
- Function
- Structure
- References
- External links
- Further reading
Ribosome biogenesis protein BOP1 is a protein that in humans is encoded by the BOP1 gene. It is a WD40 repeat-containing nucleolar protein involved in rRNA processing, thereby controlling the cell cycle. It is required for the maturation of the 25S and 5.8S ribosomal RNAs. It may serve as an essential factor in ribosome formation that coordinates processing of the spacer regions in pre-rRNA.
== Function ==
Excerpted from Wikipedia’s “BOP1” article, available under the CC BY-SA 4.0 licence.