Structure via PubChem · Public domain (PubChem)
camylofin
Sign in to saveCamylofin is an antimuscarinic drug.
Chemical data
- Formula
- C19H32N2O2
- Molecular weight
- 320.5 g/mol
- IUPAC name
- 3-methylbutyl 2-[2-(diethylamino)ethylamino]-2-phenylacetate
- SMILES
- CCN(CC)CCNC(C1=CC=CC=C1)C(=O)OCCC(C)C
- InChIKey
- RYOOHIUJEJZCFT-UHFFFAOYSA-N
- XLogP
- 3.9
- Polar surface area
- 41.6 Ų
- H-bond donors
- 1
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
- Indications
- gastrointestinal disease
via ChEMBL · EBI
Research
44 papers- Effectiveness and Safety of Camylofin in Augmentation of Labor: A Systematic Review and Meta-Analysis.Journal of obstetrics and gynaecology of India · 2020
- Antispasmodics for labour.The Cochrane database of systematic reviews · 2012
- Antispasmodics for labour.The Cochrane database of systematic reviews · 2013
- Camylofin intoxication reversed by naloxone.Lancet (London, England) · 1988
- Simultaneously quantifying a novel five-component anti- migraine formulation containing ergotamine, propyphenazone, caffeine, camylofin, and mecloxamine using UV spectrophotometry and chemometric models.BMC chemistry · 2024
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 320.246
Show 3 more facts
- chemical formula
- C₁₉H₃₂N₂O₂
- canonical SMILES
- CCN(CC)CCNC(C1=CC=CC=C1)C(=O)OCCC(C)C
- subject has role
- parasympatholytic
Sources (6)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- Synthesis
- References
Camylofin is an antimuscarinic drug.
Camylofin is a smooth muscle relaxant with both anticholinergic action and direct smooth muscle action. Anticholinergic action is produced by inhibiting the binding of acetylcholine to muscarinic receptors, but the action is less pronounced. Direct smooth muscle relaxation is achieved by inhibiting phosphodiesterase type IV, which leads to increased cyclic AMP and eventually reduced cytosolic calcium. Thus camylofin has a comprehensive action to relieve smooth muscle spasm. It is used to treat stomach ache in infants and children. Usually it is given in combination with paracetamol to treat stomach ache, as well as pyrexia. ==Synthesis== thumb|center|500px|Synthesis: Patents: Metamizole salt patents:
Excerpted from Wikipedia’s “camylofin” article, available under the CC BY-SA 4.0 licence.
Available in 7 languages
via Wikidata sitelinks · CC0