CD2BP2
Sign in to saveAlso known as FWP010, LIN1, PPP1R59, Snu40, U5-52K, CD2 (cytoplasmic tail) binding protein 2, CD2 cytoplasmic tail binding protein 2
CD2 antigen cytoplasmic tail-binding protein 2 is a protein that in humans is encoded by the CD2BP2 gene.
In the Vinony graph
Within Vinony's link graph, CD2BP2 is referenced by 4 other articles, and connects out to PubMed, human chromosome 16 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 16.
Its subject is documented across 6 Wikipedia language editions.
Gene data
CD2BP2- Name
- CD2 cytoplasmic tail binding protein 2
- Type
- protein-coding
- Position
- 30,341,365–30,355,851 (−)
- Aliases
- FWP010, LIN1, PPP1R59, Snu40, U5-52K
- Ensembl
- ENSG00000169217
- RefSeq RNA
- NM_001243646.2, NM_006110.3
- RefSeq protein
- NP_001230575.1, NP_006101.1
This gene encodes a bi-functional protein. In the cytoplasm, the encoded protein binds the cytoplasmic tail of human surface antigen CD2 via its C-terminal GYF domain, and regulate CD2-triggered T lymphocyte activation. In the nucleus, this protein is a component of the U5 small nuclear ribonucleoprotein complex and is involved in RNA splicing. A pseudogene has been identified on chromosome 7. Alternative splicing results in multiple transcript variants but their biological validity has not been determined. [provided by RefSeq, Nov 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
CD2 cytoplasmic tail binding protein 2
- Symbol
- CD2BP2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 16:30,341,365-30,355,851
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein CD2BP2 PDB 1gyf.png
Show 8 more facts
- HomoloGene ID
- 4455
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/10421
- genomic end
- 30355308
- genomic start
- 30350773
- chromosome
- human chromosome 16
- cytogenetic location
- 16p11.2
- expressed in
- gastric mucosa
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Interactions
- References
- Further reading
- External links
CD2 antigen cytoplasmic tail-binding protein 2 is a protein that in humans is encoded by the CD2BP2 gene.
==Interactions== CD2BP2 has been shown to interact with CD2.
Excerpted from Wikipedia’s “CD2BP2” article, available under the CC BY-SA 4.0 licence.