Structure via PubChem · Public domain (PubChem)
In the Vinony graph
Vinony's link graph records 185 inbound references to cefazedone, and connects out to antibiotic, ceftolozane/tazobactam and penicillin.
Vinony files it under 4-Pyridones, Cephalosporin antibiotics and Chemical pages without DrugBank identifier.
Vinony links it to 9 Wikipedia language editions.
Chemical data
- Formula
- C18H15Cl2N5O5S3
- Molecular weight
- 548.4 g/mol
- IUPAC name
- (6R,7R)-7-[[2-(3,5-dichloro-4-oxo-1-pyridinyl)acetyl]amino]-3-[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
- SMILES
- CC1=NN=C(S1)SCC2=C(N3[C@@H]([C@@H](C3=O)NC(=O)CN4C=C(C(=O)C(=C4)Cl)Cl)SC2)C(=O)O
- InChIKey
- VTLCNEGVSVJLDN-MLGOLLRUSA-N
- XLogP
- 1.1
- Polar surface area
- 212 Ų
- H-bond donors
- 2
- H-bond acceptors
- 11
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
- Indications
- bacterial disease
via ChEMBL · EBI
Research
65 papers- Bactericidal activity of cefazedone.Arzneimittel-Forschung · 1979
- [Cefazedone in infectious diseases in gynecology. Clinical tests on efficacy and tolerance].Fortschritte der Medizin · 1979
- A Pharmacokinetic and Pharmacodynamic Study on Intravenous Cefazedone Sodium in Patients with Community-acquired Pneumonia.Chinese medical journal · 2015
- Blood levels and tissue concentrations of cefazedone in animals.Arzneimittel-Forschung · 1979
- Determination of cefazedone in human plasma by high performance liquid chromatography-tandem mass spectrometry: Application to a pharmacokinetic study on Chinese volunteers.Journal of chromatography. B, Analytical technologies in the biomedical and life sciences · 2010
via PubMed
Wikidata facts
- Mass
- 546.961
Show 5 more facts
- subject has role
- antibiotic
- chemical formula
- C₁₈H₁₅Cl₂N₅O₅S₃
- isomeric SMILES
- CC1=NN=C(S1)SCC2=C(N3[C@@H]([C@@H](C3=O)NC(=O)CN4C=C(C(=O)C(=C4)Cl)Cl)SC2)C(=O)O
- canonical SMILES
- CC1=NN=C(S1)SCC2=C(N3C(C(C3=O)NC(=O)CN4C=C(C(=O)C(=C4)Cl)Cl)SC2)C(=O)O
- World Health Organisation international non-proprietary name
- cefazedone
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- External links
{{Drugbox | Watchedfields = changed | verifiedrevid = 443771825 | IUPAC_name = (6R,7R)-7-{[2-(3,5-dichloro-4-oxopyridin-1-yl)acetyl]amino}-3-[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid | image = cefazedone.png | image_class = skin-invert-image
| tradename = | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration =
Excerpted from Wikipedia’s “cefazedone” article, available under the CC BY-SA 4.0 licence.
Available in 9 languages
via Wikidata sitelinks · CC0