Structure via PubChem · Public domain (PubChem)
ceforanide
Sign in to saveAlso known as Precef, BL-S786, 7-[O-(Aminomethyl)phenylacetamido]-3-[[[1-(carboxymethyl)-1H-tetrazol-5-yl]thio]methyl]-3-cephem-4-carboxylic acid, (6R,7R)-7-[[2-[2-(Aminomethyl)phenyl]acetyl]amino]-3-[[1-(carboxymethyl)tetrazol-5-yl]sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7beta-[2-(Aminomethyl)phenyl]acetamido-3-{[1-(carboxymethyl)-1H-tetrazol-5-yl]sulfanyl}methyl-3,4-didehydrocepham-4-carboxylic acid, Ceforanido, Ceforanidum
Ceforanide is a second-generation cephalosporin antibiotic.
In the Vinony graph
Within Vinony's link graph, ceforanide is referenced by 186 other articles, and connects out to antibiotic, ceftolozane/tazobactam and kidney.
It sits within the topics Aminomethyl compounds, Cephalosporin antibiotics and Drugboxes which contain changes to verified fields.
Its subject is documented across 8 Wikipedia language editions.
Chemical data
- Formula
- C20H21N7O6S2
- Molecular weight
- 519.6 g/mol
- IUPAC name
- (6R,7R)-7-[[2-[2-(aminomethyl)phenyl]acetyl]amino]-3-[[1-(carboxymethyl)tetrazol-5-yl]sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
- SMILES
- C1C(=C(N2[C@H](S1)[C@@H](C2=O)NC(=O)CC3=CC=CC=C3CN)C(=O)O)CSC4=NN=NN4CC(=O)O
- InChIKey
- SLAYUXIURFNXPG-CRAIPNDOSA-N
- XLogP
- -3.2
- Polar surface area
- 244 Ų
- H-bond donors
- 4
- H-bond acceptors
- 12
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1984
- Admin. routes
- parenteral
- Indications
- bacterial disease
via ChEMBL · EBI
Research
90 papers- Ceforanide: antibacterial activity, pharmacology, and clinical efficacy.Pharmacotherapy · 1982
- Ceforanide. A review of its antibacterial activity, pharmacokinetic properties and clinical efficacy.Drugs · 1987
- Ceforanide kinetics.Clinical pharmacology and therapeutics · 1981
- Ceforanide kinetics in renal insufficiency.Clinical pharmacology and therapeutics · 1981
- Ceforanide (Precef).The Medical letter on drugs and therapeutics · 1984
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 519.099473
- Has use
- medication
Show 7 more facts
- chemical formula
- C₂₀H₂₁N₇O₆S₂
- subject has role
- bactericide
- canonical SMILES
- C1C(=C(N2C(S1)C(C2=O)NC(=O)CC3=CC=CC=C3CN)C(=O)O)CSC4=NN=NN4CC(=O)O
- isomeric SMILES
- C1C(=C(N2[C@H](S1)[C@@H](C2=O)NC(=O)CC3=CC=CC=C3CN)C(=O)O)CSC4=NN=NN4CC(=O)O
- World Health Organisation international non-proprietary name
- ceforanide
- defined daily dose
- 4
- Commons category
- Ceforanide
Sources (3)
via Wikidata · CC0
~2 min read
Encyclopedic overview
2 sectionsContents
- See also
- References
{{Drugbox | Verifiedfields = changed | verifiedrevid = 460023791 | IUPAC_name = (6R,7R)-7-{[2-[2-(aminomethyl)phenyl]acetyl]amino}-3-{[1-(carboxymethyl)tetrazol-5-yl]sulfanylmethyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid | image = Ceforanide.svg | image_class = skin-invert-image
| tradename = | Drugs.com = | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_UK = | legal_US = | legal_status = | routes_of_administration = Intramuscular
Excerpted from Wikipedia’s “ceforanide” article, available under the CC BY-SA 4.0 licence.
Available in 8 languages
via Wikidata sitelinks · CC0