CLDN9
Sign in to saveAlso known as claudin 9, DFNB116
Claudin-9 is a protein that in humans is encoded by the CLDN9 gene. It belongs to the group of claudins.
In the Vinony graph
Within Vinony's link graph, CLDN9 is referenced by 2 other articles, and connects out to PubMed, human chromosome 16 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 16.
Its subject is documented across 5 Wikipedia language editions.
Gene data
CLDN9- Name
- claudin 9
- Type
- protein-coding
- Position
- 3,012,923–3,014,505 (+)
- Aliases
- DFNB116
- Ensembl
- ENSG00000213937
- RefSeq RNA
- NM_020982.4
- RefSeq protein
- NP_066192.1
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This protein is one of the entry cofactors for hepatitis C virus. Mouse studies revealed that this gene is required for the preservation of sensory cells in the hearing organ and the gene deficiency is associated with deafness. [provided by RefSeq, Jun 2010].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
claudin 9
- Symbol
- CLDN9
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 16:3,012,923-3,014,505
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 10656
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/9080
- genomic end
- 3064506
- genomic start
- 3012923
- chromosome
- human chromosome 16
- cytogenetic location
- 16p13.3
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- References
- External links
- Further reading
Claudin-9 is a protein that in humans is encoded by the CLDN9 gene. It belongs to the group of claudins.
This gene is expressed in the inner ear, olfactory epithelium, and anterior pituitary gland and is involved in hearing.
Excerpted from Wikipedia’s “CLDN9” article, available under the CC BY-SA 4.0 licence.