CLDN10
Sign in to saveAlso known as CPETRL3, OSP-L, claudin 10, OSPL, HELIX
Claudin-10 is a protein that in humans is encoded by the CLDN10 gene. It belongs to the group of claudins.
In the Vinony graph
Within Vinony's link graph, CLDN10 is referenced by 3 other articles, and connects out to PubMed, human chromosome 13 and Ensembl genome database project.
It sits within the topics Biology of bipolar disorder and Genes on human chromosome 13.
Its subject is documented across 5 Wikipedia language editions.
Gene data
CLDN10- Name
- claudin 10
- Type
- protein-coding
- Position
- 95,433,594–95,603,306 (+)
- Aliases
- CPETRL3, HELIX, OSP-L, OSPL
- Ensembl
- ENSG00000134873
- RefSeq RNA
- NM_001160100.2, NM_006984.5, NM_182848.4, XM_047430765.1, XM_054375166.1
- RefSeq protein
- NP_001153572.1, NP_008915.1, NP_878268.1, XP_047286721.1, XP_054231141.1
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The expression level of this gene is associated with recurrence of primary hepatocellular carcinoma. Six alternatively spliced transcript variants encoding different isoforms have been reported, but the transcript sequences of some variants are not determined.[provided by RefSeq, Jun 2010].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
claudin 10
- Symbol
- CLDN10
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 13:95,433,594-95,603,306
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 5076
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/9071
- genomic end
- 96232013
- genomic start
- 96085858
- chromosome
- human chromosome 13
- cytogenetic location
- 13q32.1
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- References
- External links
- Further reading
Claudin-10 is a protein that in humans is encoded by the CLDN10 gene. It belongs to the group of claudins.
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Two alternatively spliced transcript variants that encode different isoforms have been identified for this gene.
Excerpted from Wikipedia’s “CLDN10” article, available under the CC BY-SA 4.0 licence.