Also known as carboxypeptidase M, Carboxypeptidase M
protein-coding gene in the species Homo sapiens
Gene data
CPM- Name
- carboxypeptidase M
- Type
- protein-coding
- Position
- 68,842,197–68,971,570 (−)
- Ensembl
- ENSG00000135678
- RefSeq RNA
- NM_001005502.3, NM_001413387.1, NM_001413388.1, NM_001413389.1, NM_001413390.1
- RefSeq protein
- NP_001005502.1, NP_001400316.1, NP_001400317.1, NP_001400318.1, NP_001400319.1
The protein encoded by this gene is a membrane-bound arginine/lysine carboxypeptidase. Its expression is associated with monocyte to macrophage differentiation. This encoded protein contains hydrophobic regions at the amino and carboxy termini and has 6 potential asparagine-linked glycosylation sites. The active site residues of carboxypeptidases A and B are conserved in this protein. Three alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
carboxypeptidase M
- Symbol
- CPM
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 12:68,842,192-68,971,570
- Strand
- Reverse (−)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein CPM PDB 1uwy.png
Show 6 more facts
- HomoloGene ID
- 35367
- exact match
- identifiers.org/ncbigene/1368
- genomic end
- 69365350
- genomic start
- 69235977
- cytogenetic location
- 12q15
- EC enzyme number
- 3.4.17.12
Sources (4)
via Wikidata · CC0
Connections
Q180686
Entity
Q229883
Entity
Ensembl genome database project
Entity
International Standard Book Number
Entity
enzyme
Entity
Wikidata
Entity
gene
Entity
chromosome
Entity
digital object identifier
Entity
catalysis
Entity
peptide
Entity
L-arginine
Entity
monocyte
Entity
DL-lysine
Entity
National Center for Biotechnology Information
Entity
DL-asparagine
Entity
CAS Registry Number
Entity
macrophage
Entity
human genome
Entity
base pair
Entity