DCDC2

Also known as DCDC2A, DFNB66, NPHP19, RU2, RU2S, doublecortin domain containing 2, NSC

Doublecortin domain-containing protein 2 (DCDC2) is a protein that in humans is encoded by the DCDC2 gene.

Gene data

DCDC2

Name: doublecortin domain containing 2
Type: protein-coding
Aliases: DCDC2A, DFNB66, NPHP19, NSC, RU2, RU2S

This gene encodes a doublecortin domain-containing family member. The doublecortin domain has been demonstrated to bind tubulin and enhance microtubule polymerization. This family member is thought to function in neuronal migration where it may affect the signaling of primary cilia. Mutations in this gene have been associated with reading disability (RD) type 2, also referred to as developmental dyslexia. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jan 2013].

via MyGene.info

Gene · Ensembl

doublecortin domain containing 2

Symbol: DCDC2
Biotype: Protein coding
Organism: Homo sapiens
Location: 6:24,171,747-24,383,300
Strand: Reverse (−)
Assembly: GRCh38

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via Ensembl · EMBL-EBI

Wikidata facts

Image: Protein DCDC2 PDB 2dnf.png

Show 5 more facts

HomoloGene ID: 9483
exact match: identifiers.org/ncbigene/51473
genomic end: 24358059
genomic start: 24171755
cytogenetic location: 6p22.3

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Article

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Contents

Function
Clinical significance
References
Further reading

Doublecortin domain-containing protein 2 (DCDC2) is a protein that in humans is encoded by the DCDC2 gene.

== Function == This gene encodes a protein with two doublecortin peptide domains. This domain has been demonstrated to bind tubulin and enhance microtubule polymerization.