DDOST
Sign in to saveAlso known as AGER1, CDG1R, OKSWcl45, OST, OST48, WBP1, dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit, GATD6
Dolichyl-diphosphooligosaccharide—protein glycosyltransferase 48 kDa subunit is an enzyme that in humans is encoded by the DDOST gene.
Gene data
DDOST- Name
- dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit
- Type
- protein-coding
- Aliases
- AGER1, CDG1R, GATD6, OKSWcl45, OST, OST48, WBP1
This gene encodes a component of the oligosaccharyltransferase complex which catalyzes the transfer of high-mannose oligosaccharides to asparagine residues on nascent polypeptides in the lumen of the rough endoplasmic reticulum. The protein complex co-purifies with ribosomes. The product of this gene is also implicated in the processing of advanced glycation endproducts (AGEs), which form from non-enzymatic reactions between sugars and proteins or lipids and are associated with aging and hyperglycemia. [provided by RefSeq, Jul 2008].
via MyGene.info
Gene · Ensembl
dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit
- Symbol
- DDOST
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:20,647,467-20,661,544
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 3821
- exact match
- identifiers.org/ncbigene/1650
- genomic end
- 20988000
- genomic start
- 20978270
- cytogenetic location
- 1p36.12
Sources (4)
via Wikidata · CC0
~1 min read
Article
2 sectionsContents
- References
- Further reading
Dolichyl-diphosphooligosaccharide—protein glycosyltransferase 48 kDa subunit is an enzyme that in humans is encoded by the DDOST gene.
This gene encodes a component of the oligosaccharyltransferase complex which catalyzes the transfer of high-mannose oligosaccharides to asparagine residues on nascent polypeptides in the lumen of the rough endoplasmic reticulum. The protein complex co-purifies with ribosomes. The product of this gene is also implicated in the processing of advanced glycation endproducts (AGEs), which form from non-enzymatic reactions between sugars and proteins or lipids and are associated with aging and hyperglycemia.