DEF6
Sign in to saveAlso known as IBP, SLAT, SWAP70L, DEF6, guanine nucleotide exchange factor, DEF6 guanine nucleotide exchange factor, IMD87
Differentially expressed in FDCP 6 homolog is a protein that in humans is encoded by the DEF6 gene.
Gene data
DEF6- Name
- DEF6 guanine nucleotide exchange factor
- Type
- protein-coding
- Position
- 35,297,818–35,321,909 (+)
- Aliases
- IBP, IMD87, SLAT, SWAP70L
- Ensembl
- ENSG00000023892
- RefSeq RNA
- NM_022047.4, XM_047418838.1, XM_054355531.1
- RefSeq protein
- NP_071330.3, XP_047274794.1, XP_054211506.1
DEF6, or IBP, is a guanine nucleotide exchange factor (GEF) for RAC (MIM 602048) and CDC42 (MIM 116952) that is highly expressed in B and T cells (Gupta et al., 2003 [PubMed 12923183]).[supplied by OMIM, Mar 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
DEF6 guanine nucleotide exchange factor
- Symbol
- DEF6
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 6:35,297,818-35,321,909
- Strand
- Forward (+)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 11103
- exact match
- identifiers.org/ncbigene/50619
- genomic start
- 35297818
- genomic end
- 35289548
- cytogenetic location
- 6p21.31
Sources (4)
via Wikidata · CC0
~1 min read
Article
2 sectionsContents
- References
- Further reading
Differentially expressed in FDCP 6 homolog is a protein that in humans is encoded by the DEF6 gene.
== References ==
Connections
Q180686
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human chromosome 6
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Ensembl genome database project
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protein
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