PARD6A
Sign in to saveAlso known as PAR-6A, PAR6, PAR6C, PAR6alpha, TAX40, TIP-40, par-6 family cell polarity regulator alpha
Partitioning defective 6 homolog alpha is a protein that in humans is encoded by the PARD6A gene.
In the Vinony graph
Vinony's link graph records 7 inbound references to PARD6A, and connects out to PubMed, human chromosome 16 and Ensembl genome database project.
Vinony files it under Genes on human chromosome 16 and Long stubs with short prose.
Vinony links it to 5 Wikipedia language editions.
Gene data
PARD6A- Name
- par-6 family cell polarity regulator alpha
- Type
- protein-coding
- Position
- 67,660,350–67,664,266 (+)
- Aliases
- PAR-6A, PAR6, PAR6C, PAR6alpha, TAX40, TIP-40
- Ensembl
- ENSG00000102981
- RefSeq RNA
- NM_001037281.2, NM_016948.3, XM_005255977.4, XM_011523095.3, XM_047434186.1
- RefSeq protein
- NP_001032358.1, NP_058644.1, XP_005256034.1, XP_011521397.1, XP_047290142.1
This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cell membrane protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. The protein also has a role in the epithelial-to-mesenchymal transition (EMT) that characterizes the invasive phenotype associated with metastatic carcinomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
par-6 family cell polarity regulator alpha
- Symbol
- PARD6A
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 16:67,660,350-67,664,266
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein PARD6A PDB 1wmh.png
Show 8 more facts
- found in taxon
- Homo sapiens
- HomoloGene ID
- 9661
- exact match
- identifiers.org/ncbigene/50855
- genomic end
- 67662774
- genomic start
- 67694849
- chromosome
- human chromosome 16
- cytogenetic location
- 16q22.1
- expressed in
- triceps brachii muscle
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Function
- Interactions
- References
- Further reading
Partitioning defective 6 homolog alpha is a protein that in humans is encoded by the PARD6A gene.
== Function ==
Excerpted from Wikipedia’s “PARD6A” article, available under the CC BY-SA 4.0 licence.