Also known as PAR-6A, PAR6, PAR6C, PAR6alpha, TAX40, TIP-40, par-6 family cell polarity regulator alpha
Partitioning defective 6 homolog alpha is a protein that in humans is encoded by the PARD6A gene.
This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cell membrane protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. The protein also has a role in the epithelial-to-mesenchymal transition (EMT) that characterizes the invasive phenotype associated with metastatic carcinomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].
via MyGene.info
Partitioning defective 6 homolog alpha is a protein that in humans is encoded by the PARD6A gene.
== Function ==
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Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).