Skip to content
ProteinQ21113034· pop 10· linked from 360 articles

CD6 molecule

Sign in to save

Also known as CD6, TP120, CD6 antigen, T-cell differentiation antigen CD6, T12

CD6 (Cluster of Differentiation 6) is a human protein encoded by the gene.

Protein · UniProt

T-cell differentiation antigen CD6

Gene
CD6
Organism
Homo sapiens (Human)
Length
668 aa
Molecular mass
71,801 Da
Evidence
1: Evidence at protein level

Cell adhesion molecule that mediates cell-cell contacts and regulates T-cell responses via its interaction with ALCAM/CD166 (PubMed:15048703, PubMed:15294938, PubMed:16352806, PubMed:16914752, PubMed:24584089, PubMed:24945728). Contributes to signaling cascades triggered by activation of the TCR/CD3 complex (PubMed:24584089). Functions as a costimulatory molecule; promotes T-cell activation and proliferation (PubMed:15294938, PubMed:16352806, PubMed:16914752). Contributes to the formation and maturation of the immunological synapse (PubMed:15294938, PubMed:16352806). Functions as a calcium-…

3D-structureAdaptive immunityAlternative splicingCell adhesionCell membraneDisulfide bondGlycoproteinImmunity
View on UniProt →

Swiss-Prot (reviewed) · via UniProt

Wikidata facts

Show 1 more fact
Sources (4)

via Wikidata · CC0

~1 min read

Article

6 sections
Contents
  • Function
  • Clinical significance
  • See also
  • References
  • Further reading
  • External links

CD6 (Cluster of Differentiation 6) is a human protein encoded by the gene.

== Function ==

Available in 10 languages

via Wikidata sitelinks · CC0

Connections

Categories