detomidine

Detomidine is an imidazole derivative and α2-adrenergic receptor agonist, used as a large animal sedative, primarily used in horses. It is usually available as the salt detomidine hydrochloride. It is a prescription medication available to veterinarians sold under various trade names.

In the Vinony graph

Within Vinony's link graph, detomidine is referenced by 822 other articles, and connects out to propranolol, atenolol and adrenergic receptor.

It is catalogued under topics including Alpha2-adrenergic agonists, Chemical pages without DrugBank identifier and Drugboxes which contain changes to verified fields.

Its subject is documented across 9 Wikipedia language editions.

Chemical data

Formula: C12H14N2
Molecular weight: 186.25 g/mol
IUPAC name: 5-[(2,3-dimethylphenyl)methyl]-1H-imidazole
SMILES: CC1=C(C(=CC=C1)CC2=CN=CN2)C
InChIKey: RHDJRPPFURBGLQ-UHFFFAOYSA-N
XLogP: 2.7
Polar surface area: 28.7 Å²
H-bond donors: 1
H-bond acceptors: 1
Formal charge: 0

via PubChem

Drug data · ChEMBL

Max clinical phase: Phase 2
Molecule type: Small molecule

via ChEMBL · EBI

Research

533 papers

via PubMed

Wikidata facts

Subclass of: chemical compound
Mass: 186.116

Show 2 more facts

chemical formula: C₁₂H₁₄N₂
canonical SMILES: CC1=C(C(=CC=C1)CC2=CN=CN2)C

Sources (5)

via Wikidata · CC0

~2 min read

Encyclopedic overview

6 sections

Contents

Use
Properties
Pharmacology
Veterinary use
References
External links

==Use== Currently, detomidine is licensed for use only in non-meat horses in the United States, but it is also licensed for use in cattle in Europe and Australia. Detomidine's withholding period is 12–72 hours for dairy cattle and 2–3 days for meat cattle.

Excerpted from Wikipedia’s “detomidine” article, available under the CC BY-SA 4.0 licence.