indanidine

Chemical data

Formula

C11H13N5

Molecular weight

215.25 g/mol

IUPAC name

N-(4,5-dihydro-1H-imidazol-2-yl)-2-methylindazol-4-amine

SMILES

CN1C=C2C(=N1)C=CC=C2NC3=NCCN3

InChIKey

PNHJTLDBYZVCGW-UHFFFAOYSA-N

XLogP

0.3

Polar surface area

54.2 Ų

H-bond donors

2

H-bond acceptors

2

Formal charge

0

via PubChem

Drug data · ChEMBL

Max clinical phase

Phase 2

Molecule type

Small molecule

via ChEMBL · EBI

• Systemic and regional hemodynamic characterization of alpha-1 and alpha-2 adrenoceptor agonists in pithed rats.The Journal of pharmacology and experimental therapeutics · 1987
• Analysis of the action of idazoxan calls into question the reliability of the rat isolated small mesenteric artery assay as a predictor for alpha 1-adrenoceptor-mediated pressor activity.Naunyn-Schmiedeberg's archives of pharmacology · 1996
• Blockade by nifedipine of responses to intravenous bolus injection or infusion of alpha 1- and alpha 2-adrenoceptor agonists in the pithed rat.British journal of pharmacology · 1987
• Functional evidence for an alpha 1B-adrenoceptor mediating contraction of the mouse spleen.European journal of pharmacology · 1996
• alpha-Adrenoceptor agonists and the Ca2+-dependence of smooth muscle contraction: evidence for subtypes of receptors or for agonist-dependent differences in the agonist-receptor interaction?Clinical science (London, England : 1979) · 1985

via PubMed

Wikidata facts

Subclass of

chemical compound

Mass

215.117095

via Wikidata · CC0