metomidate

Metomidate is a non-barbiturate imidazole that was discovered by Janssen Pharmaceutica in 1965 and under the names (Hypnodil, Nokemyl) is sold as a sedative-hypnotic drug used in Europe to treat humans and for veterinary purposes.

Research

181 papers

(11)C-metomidate PET in the diagnosis of adrenal masses and primary aldosteronism: a review of the literature.Endocrine · 2020
[(11)C]metomidate PET-CT versus adrenal vein sampling for diagnosing surgically curable primary aldosteronism: a prospective, within-patient trial.Nature medicine · 2023
Metomidate-based imaging of adrenal masses.Hormones & cancer · 2011
Lateralization in (11) C-Metomidate PET and outcome of adrenalectomy in primary aldosteronism.Endocrinology, diabetes & metabolism · 2022
The Role of GABA Receptors in Anesthesia and Sedation: An Updated Review.CNS drugs · 2025

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Wikidata facts

Mass: 230.106

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canonical SMILES: CC(C1=CC=CC=C1)N2C=NC=C2C(=O)OC
chemical formula: C₁₃H₁₄N₂O₂

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References

11C-labelled metomidate (11C-metomidate), may be used with positron emission tomography (PET). For instance, to detect tumors of adrenocortical origin.