Structure via PubChem · Public domain (PubChem)
metofoline
Sign in to saveAlso known as methofoline
Metofoline (INN), also known as methofoline (USAN), is an opioid analgesic drug discovered in the 1950s by a team of Swiss researchers at Hoffmann-La Roche.
In the Vinony graph
Vinony's link graph records 5 inbound references to metofoline, and connects out to (+)-catechin, butorphanol and International Standard Book Number.
It sits within the topics 4-Chlorophenyl compounds, Abandoned drugs and Chemical pages without DrugBank identifier.
Vinony links it to 5 Wikipedia language editions.
Chemical data
- Formula
- C20H24ClNO2
- Molecular weight
- 345.9 g/mol
- IUPAC name
- 1-[2-(4-chlorophenyl)ethyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinoline
- SMILES
- CN1CCC2=CC(=C(C=C2C1CCC3=CC=C(C=C3)Cl)OC)OC
- InChIKey
- YBCPYHQFUMNOJG-UHFFFAOYSA-N
- XLogP
- 4.7
- Polar surface area
- 21.7 Ų
- H-bond donors
- 0
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
Withdrawn- Max clinical phase
- Approved
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 345.149557
Show 2 more facts
- chemical formula
- C₂₀H₂₄ClNO₂
- canonical SMILES
- CN1CCC2=CC(=C(C=C2C1CCC3=CC=C(C=C3)Cl)OC)OC
Sources (2)
via Wikidata · CC0
~2 min read
Encyclopedic overview
2 sectionsContents
- See also
- References
Metofoline (INN), also known as methofoline (USAN), is an opioid analgesic drug discovered in the 1950s by a team of Swiss researchers at Hoffmann-La Roche.
Methopholine is an isoquinoline derivative which is not structurally related to most other opioids. However, its structural similarity to the non-opioid alkaloid papaverine is notable.
Excerpted from Wikipedia’s “metofoline” article, available under the CC BY-SA 4.0 licence.