Structure via PubChem · Public domain (PubChem)
proparacaine
Sign in to saveAlso known as Alcaine®, Paracaine®, proparacaine hydrochloride, proxymetacaine hydrochloride, Proxymetacaine, Proxymetacainum, Proximetacaina
Proxymetacaine (INN) or proparacaine (USAN) is a topical anesthetic drug of the aminoester group.
In the Vinony graph
Within Vinony's link graph, proparacaine is referenced by 381 other articles, and connects out to local anesthetic, International Standard Book Number and cocaine.
It sits within the topics Anilines, Benzoate esters and Diethylamino compounds.
Its subject is documented across 11 Wikipedia language editions.
Chemical data
- Formula
- C16H26N2O3
- Molecular weight
- 294.39 g/mol
- IUPAC name
- 2-(diethylamino)ethyl 3-amino-4-propoxybenzoate
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1953
- Admin. routes
- topical
- Indications
- pain
via ChEMBL · EBI
Research
444 papers- An Analysis of the Use of Proparacaine in Cataract Surgery.Cureus · 2022
- Proparacaine-Induced Mydriasis During Strabismus Surgery.Seminars in ophthalmology · 2018
- Therapeutic Approach for Trigeminal Neuralgia: A Systematic Review.Biomedicines · 2023
- Proparacaine Overuse in Corneal Abrasions at the Emergency Department: A Case Series.Eye & contact lens · 2024
- Comparison of Proparacaine, Tetracaine, and Oxybuprocaine in Corneal Sensitivity Measurement.Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics · 2024
via PubMed
Wikidata facts
- Subclass of
- local anesthetic
- Mass
- 294.194343
- Has use
- medication
Show 3 more facts
- chemical formula
- C₁₆H₂₆N₂O₃
- canonical SMILES
- CCCOC1=C(C=C(C=C1)C(=O)OCCN(CC)CC)N
- subject has role
- local anesthetic
Sources (2)
via Wikidata · CC0
~2 min read
Encyclopedic overview
6 sectionsContents
- Clinical pharmacology
- Mechanism of action
- Indications and usage
- Warnings
- How supplied
- References
Proxymetacaine (INN) or proparacaine (USAN) is a topical anesthetic drug of the aminoester group.
==Clinical pharmacology== Proxymetacaine is a local anesthetic which on topical application penetrates sensory nerve endings in the corneal tissue.
Excerpted from Wikipedia’s “proparacaine” article, available under the CC BY-SA 4.0 licence.
Available in 11 languages
via Wikidata sitelinks · CC0