drotrecogin alfa
Sign in to saveAlso known as drotrecogin alfa (activated), lyophilized, Autoprothrombin IIA, activated protein c, drotrecoginum alfa (activatum), Vitamin K-dependent protein C precursor, blood coagulation factor xiv (human), ly203638, drotrecogin
pharmaceutical drug
In the Vinony graph
Vinony's link graph records 205 inbound references to drotrecogin alfa, and connects out to intravenous infusion and defusion, hirudin and coagulation factor X.
It sits within the topics Antithrombotic enzymes, Chemicals that do not have a ChemSpider ID assigned and Drugboxes which contain changes to verified fields.
Vinony links it to 7 Wikipedia language editions.
Chemical data
Drug data · ChEMBL
Withdrawn- Max clinical phase
- Approved
- Molecule type
- Protein
- First approval
- 2001
- Admin. routes
- parenteral
- Indications
- chronic kidney disease, Recurrent thrombophlebitis, pulmonary embolism, Sepsis
via ChEMBL · EBI
Research
744 papers- Drotrecogin alfa.Drugs of today (Barcelona, Spain : 1998) · 2004
- Drotrecogin alfa (activated).Drugs · 2002
- Drotrecogin alfa (activated) for the treatment of severe sepsis and septic shock.The American journal of the medical sciences · 2004
- Drotrecogin alfa (activated) (recombinant human activated protein C) for the treatment of severe sepsis.Critical care medicine · 2003
- Drotrecogin alfa (activated) in adults with septic shock.The New England journal of medicine · 2012
via PubMed
Wikidata facts
- Official website
- www.xigris.com
- Has use
- medication
Show 4 more facts
- medical condition treated
- sepsis
- NCI Thesaurus ID
- C80267
- defined daily dose
- 40
- has characteristic
- biopharmaceutical
via Wikidata · CC0