Structure via PubChem · Public domain (PubChem)
tioclomarol
Sign in to saveAlso known as Apegmone, 3-[3-(4-chlorophenyl)-1-(5-chlorothiophen-2-yl)-3-hydroxypropyl]-4-hydroxychromen-2-one
Tioclomarol is an anticoagulant of the 4-hydroxycoumarin vitamin K antagonist type. It is a second generation drug, used as a rodenticide that is effective for the control of rodents that are resistant to this class of drugs.
In the Vinony graph
Within Vinony's link graph, tioclomarol is referenced by 115 other articles, and connects out to hirudin, coagulation factor X and ximelagatran.
It sits within the topics 4-Chlorophenyl compounds, Chemical pages without DrugBank identifier and Chloroarenes.
Its subject is documented across 6 Wikipedia language editions.
Chemical data
- Formula
- C22H16Cl2O4S
- Molecular weight
- 447.3 g/mol
- IUPAC name
- 3-[3-(4-chlorophenyl)-1-(5-chlorothiophen-2-yl)-3-hydroxypropyl]-2-hydroxychromen-4-one
- SMILES
- C1=CC=C2C(=C1)C(=O)C(=C(O2)O)C(CC(C3=CC=C(C=C3)Cl)O)C4=CC=C(S4)Cl
- InChIKey
- XGZCHPQWRLBXDZ-UHFFFAOYSA-N
- XLogP
- 5.6
- Polar surface area
- 95 Ų
- H-bond donors
- 2
- H-bond acceptors
- 5
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
- Indications
- Recurrent thrombophlebitis
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 446.0146353519999
- Has use
- medication
Show 2 more facts
- chemical formula
- C₂₂H₁₆Cl₂SO₄
- canonical SMILES
- C1=CC=C2C(=C1)C(=C(C(=O)O2)C(CC(C3=CC=C(C=C3)Cl)O)C4=CC=C(S4)Cl)O
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
Tioclomarol is an anticoagulant of the 4-hydroxycoumarin vitamin K antagonist type. It is a second generation drug, used as a rodenticide that is effective for the control of rodents that are resistant to this class of drugs.
==References==
Excerpted from Wikipedia’s “tioclomarol” article, available under the CC BY-SA 4.0 licence.