English
elinogrel
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Elinogrel (INN, USAN) was an experimental antiplatelet drug acting as a P2Y12 inhibitor. Similarly to ticagrelor and in contrast to clopidogrel, elinogrel was a reversible inhibitor that acted fast and short (for about 12 hours), and it was not a prodrug but pharmacologically active itself. The substance was used in form of its potassium salt, intravenously for acute treatment and orally for long-term treatment. Development was terminated in 2012.
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 523.019
Show 3 more facts
- chemical formula
- C₂₀H₁₅ClFN₅O₅S₂
- canonical SMILES
- CNC1=C(C=C2C(=C1)NC(=O)N(C2=O)C3=CC=C(C=C3)NC(=O)NS(=O)(=O)C4=CC=C(S4)Cl)F
- World Health Organisation international non-proprietary name
- elinogrel
via Wikidata · CC0
~2 min read
Encyclopedic overview
2 sectionsContents
- History
- References
{{Drugbox | IUPAC_name = N-[(5-Chlorothiophen-2-yl)sulfonyl]-N′-{4-[6-fluoro-7-(methylamino)-2,4-dioxo-1,4-dihydroquinazolin-3(2H)-yl]phenyl}urea | image = Elinogrel skeletal.svg | image_class = skin-invert-image | width = 275
| tradename = | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = Development terminated | routes_of_administration = By mouth, IV
Excerpted from Wikipedia’s “elinogrel” article, available under the CC BY-SA 4.0 licence.