entecavir

Also known as BMS-200475-01, SQ-34676, Entecavir anhydrous, Entecavirum, Anhydrous entecavir, Entecavir (anhydrous)

Entecavir, sold under the brand name Baraclude, is an antiviral medication used in the treatment of hepatitis B virus infection. In those with both HIV/AIDS and hepatitis B virus antiretroviral medication should also be used. Entecavir is taken by mouth as a tablet or solution.

Key facts

Drug.Verifiedfields: changed
Drug.Watchedfields: changed
Drug.verifiedrevid: 464189683
Drug.image: Entecavir structure.svg
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Drug.width: 240
Drug.image2: Entecavir ball-and-stick model.png
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Drug.tradename: Baraclude, others
Drug.MedlinePlus: a605028
Drug.DailyMedID: Entecavir
Drug.pregnancy_AU: B3
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Article

8 sections

Contents

Medical uses
Pregnancy and breastfeeding
Side effects
Mechanism of action
Administration
History
Patent information
References

Common side effects include headache, nausea, high blood sugar, and decreased kidney function. Severe side effects include enlargement of the liver, high blood lactate levels, and liver inflammation if the medication is stopped. While there appears to be no harm from use during pregnancy, this use has not been well studied. Entecavir is in the nucleoside reverse transcriptase inhibitors (NRTIs) family of medications. It prevents the hepatitis B virus from multiplying by blocking reverse transcriptase.