Structure via PubChem · Public domain (PubChem)
etoperidone
Sign in to saveAlso known as Triazolinone, Clopradone
Etoperidone, associated with several brand names, is an atypical antidepressant which was developed in the 1970s and either is no longer marketed or was never marketed. It is a phenylpiperazine related to trazodone and nefazodone in chemical structure and is a serotonin antagonist and reuptake inhibitor (SARI) similarly to them.
In the Vinony graph
Vinony's link graph records 2,408 inbound references to etoperidone, and connects out to propranolol, N-methylserotonin and lysergic acid diethylamide.
It is catalogued under topics including 1,2,4-Triazol-3-ones, 1-Phenylpiperazines and 3-Chlorophenyl compounds.
Vinony links it to 9 Wikipedia language editions.
Chemical data
- Formula
- C19H28ClN5O
- Molecular weight
- 377.9 g/mol
- IUPAC name
- 2-[3-[4-(3-chlorophenyl)piperazin-1-yl]propyl]-4,5-diethyl-1,2,4-triazol-3-one
- SMILES
- CCC1=NN(C(=O)N1CC)CCCN2CCN(CC2)C3=CC(=CC=C3)Cl
- InChIKey
- IZBNNCFOBMGTQX-UHFFFAOYSA-N
- XLogP
- 3
- Polar surface area
- 42.4 Ų
- H-bond donors
- 0
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
- Indications
- major depressive disorder
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 377.198238
- Has use
- medication
Show 3 more facts
- chemical formula
- C₁₉H₂₈ClN₅O
- canonical SMILES
- CCC1=NN(C(=O)N1CC)CCCN2CCN(CC2)C3=CC(=CC=C3)Cl
- Commons category
- Etoperidone
Sources (2)
via Wikidata · CC0
~4 min read
Encyclopedic overview
13 sectionsContents
- Medical uses
- Pharmacology
- Pharmacodynamics
- Pharmacokinetics
- Chemistry
- History
- Society and culture
- Generic names
- Brand names
- Research
- See also
- References
- External links
Etoperidone, associated with several brand names, is an atypical antidepressant which was developed in the 1970s and either is no longer marketed or was never marketed. It is a phenylpiperazine related to trazodone and nefazodone in chemical structure and is a serotonin antagonist and reuptake inhibitor (SARI) similarly to them.
==Medical uses== Etoperidone was used or was intended for use as an antidepressant in the treatment of depression.
Excerpted from Wikipedia’s “etoperidone” article, available under the CC BY-SA 4.0 licence.