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GeneQ18037637· pop 5· linked from 9 articles

Also known as HH21, fibronectin leucine rich transmembrane protein 3

Leucine-rich repeat transmembrane protein FLRT3 is a protein that in humans is encoded by the FLRT3 gene.

Gene data

FLRT3
Name
fibronectin leucine rich transmembrane protein 3
Type
protein-coding
Aliases
HH21

This gene encodes a member of the fibronectin leucine rich transmembrane protein (FLRT) family. FLRTs may function in cell adhesion and/or receptor signalling. Their protein structures resemble small leucine-rich proteoglycans found in the extracellular matrix. This gene is expressed in many tissues. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq, Jul 2010].

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Gene · Ensembl

fibronectin leucine rich transmembrane protein 3

Symbol
FLRT3
Biotype
Protein coding
Organism
Homo sapiens
Location
20:14,322,538-14,337,643
Strand
Reverse (−)
Assembly
GRCh38
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via Ensembl · EMBL-EBI

Wikidata facts

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HomoloGene ID
8322
genomic end
14337614
genomic start
14322985
cytogenetic location
20p12.1
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Leucine-rich repeat transmembrane protein FLRT3 is a protein that in humans is encoded by the FLRT3 gene.

FLRT1, FLRT2 and FLRT3 are members of the fibronectin leucine rich transmembrane protein (FLRT) family. They may function in cell adhesion and/or receptor signalling. Their protein structures resemble small leucine-rich proteoglycans found in the extracellular matrix. FLRT3 shares 55% amino acid sequence identity with FLRT1 and 44% identity with FLRT2. FLRT3 is expressed in kidney, brain, pancreas, skeletal muscle, lung, liver, placenta, and heart. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.

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