呋咯地辛

Also known as BCX-1777, BCX1777, Fodosine® (proposed trade name), immucillin H, immucillin-H, (2R,3R,4S,5S)-2-(hydroxymethyl)-5-(4-hydroxy-5H-pyrrolo[3,2-d]pyrimidin-7-yl)pyrrolidine-3,4-diol, Forodesine, (1S)-1,4-dideoxy-4-imino-(9-deazahypoxanthin-9-yl)-D-ribitol

化合物

In the Vinony graph

Within Vinony's link graph, 呋咯地辛 is referenced by 5 other articles, and connects out to digital object identifier, chemical formula and molar mass.

It is catalogued under topics including Chemical pages without DrugBank identifier, Drugs missing an ATC code and Drugs with no legal status.

Its subject is documented across 8 Wikipedia language editions.

Chemical data

Formula: C11H14N4O4
Molecular weight: 266.25 g/mol
IUPAC name: 7-[(2S,3S,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)pyrrolidin-2-yl]-1,5-dihydropyrrolo[3,2-d]pyrimidin-4-one
SMILES: C1=C(C2=C(N1)C(=O)N=CN2)[C@H]3[C@@H]([C@@H]([C@H](N3)CO)O)O
InChIKey: IWKXDMQDITUYRK-KUBHLMPHSA-N
XLogP: -2.3
Polar surface area: 130 Å²
H-bond donors: 6
H-bond acceptors: 5
Formal charge: 0

via PubChem

Drug data · ChEMBL

Max clinical phase: Approved
Molecule type: Small molecule
First approval: 2017
Indications: B-cell acute lymphoblastic leukemia, chronic lymphocytic leukemia, leukemia, lymphoma

via ChEMBL · EBI

Wikidata facts

Subclass of: chemical compound
Mass: 266.102

Show 4 more facts

chemical formula: C₁₁H₁₄N₄O₄
isomeric SMILES: C1=C(C2=C(N1)C(=O)N=CN2)[C@H]3[C@@H]([C@@H]([C@H](N3)CO)O)O
canonical SMILES: C1=C(C2=C(N1)C(=O)N=CN2)C3C(C(C(N3)CO)O)O
Commons category: Immucillin H

Sources (2)

via Wikidata · CC0